Omega 3 with vitamine D3

The kind of fat your body needs!

This mighty supplement provides an abundance of omega-3 fatty acids and vitamin D3 in order to support cardiovascular, bone, brain and immune health––so the only thing you break is barriers.*

Mannatech’s Omega-3 with Vitamin D3:

Has a pleasant lemon flavor in an easy-to-swallow gel capsule.
Helps support cardiovascular and heart health.*
Helps support brain health and function.*
Helps maintain a healthy immune system and support a healthy inflammatory response—a key contributor to good health.*
Provides support for healthy triglyceride levels already within normal levels.*
Supports calcium absorption.*
Has over 1,000 mg of highly concentrated EPA and DHA per serving.
Is made from one of the highest-quality fish oils available, for ultra-purity.
Has 830 IU of vitamin D3 , a natural and preferred form of vitamin D.

Order now

Omega 3 fishoil with with Vitamine D3

Omega 3 is considered essential because the body can not create it. You can get it only from food or from supplements. Omega-3 capsules containing Vitamin D₃ Mannatech are an excellent choice. They contain:

More than 1000 mg of highly concentrated EPA and DHA per serving.
They are made of the fish oil of the best quality that is available for an ultimate purity.
A pleasant orange flavor in a capsule which can be easily swallowed.
Contains 4 mcg of vitamin D₃, a natural and preferred source of vitamin D.

Omega 3 fish oil with vitamin D3 Mannatech is a very unique dietary supplement. EPA and DHA fatty acids in omega 3 fish oil contribute to the normal function of the brains and heart. Scientific studies have shown that populations that eat a lot of omega 3 have a lower health risks than our diets that are present in our modern Western diet.

A deficiency of omega 3 and vitamin D is becoming more common. For vitamin D we need an active outdoor life. But in our office-and-car-lives we find ourselves much inside.

Omega-3 with Vitamin D3 Mannatech:

Provides over 1,110 mg of highly concentrated EPA and DHA per serving
Made from the highest quality fish oils, molecularly distilled for ultra purity.
Made from fresh, cold water fish (not farmed) salmon, herring, mackerel, anchovies and sardines.
4mcg contains vitamin D3 per serving (830 UIs)
Easy to swallow gel capsules with a pleasant orange flavor.

Omega 3 fishoil with Vitamine D3:

DHA contributes to the maintenance of normal vision
EPA and DHA contributes to the normal functioning of the heart
DHA contributes to the maintenance of normal brain function.
Vitamin D contributes to a normal recording and processing of calcium and phosphorus.
Vitamin D contributes to the maintenance of normal bone and teeth.
Vitamin D contributes to the normal function of the immune system.

Omega 3 fatty acid from fish oil is an unsaturated fatty acid that your body needs to help maintain healthy levels of cholesterol and blood triglyceride. These are both important for the maintenance of good health. The fatty acid Omega 3 appears in different species, but there are two of which one knows that they are the most important. These are EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid).

By adding Omega 3 fish oil fatty acids to your daily diet, you will improve your overall health. In the past people ate enough Omega 3. Omega 6 is also important, but unfortunately it competes with Omega 3 for space in your cells. Instead of a balance between the two (which is optimum for your health) our modern diet consists of a ratio of up to 30: 1 omega-6 to omega 3. This imbalance condition gives a lot of general health problems. These are caused by our Western diet. In comparison, our ancestors held a ratio of 1:1.

Your body does not produce Omega 3 so you need to supplement it. Some types of fish are rich in omega 3, but unfortunately pollution and poisons form a major problem within the fish. Farmed fish are often feed grain and contain more omega 6 than omega 3. You can also get a small amount of Omega 3 from flax seed, but your body needs this form of ALA Omega-3 convert to the more advantageous EPA / DHA. Unfortunately, our bodies are not good at this. It is almost impossible to get enough EPA / DHA from flax seeds. Fish oil supplements are an excellent way to meet your daily intake, and also ensure the most EPA and DHA for the worth of your money.

Omega 3 Mannatech is a very clean and pure product. Especially in combination with Ambrotose and Nutriverus Omega 3 essential to keep your health arrow.

NSF-certified
Naturally gluten-free
Gluten-free
Reduced [fishy reflux/fishy burps]
Our fish oil concentrate is processed by high vacuum molecular distillation
Mannatech fish oils are purified to [reduce/minimize] contaminants common in natural fish oils
Produced according to pharmaceutical standards
Values for [oxidation/contaminants/pollutants] are well below those set by international regulatory standards, e.g. the European Pharmacopeia and the Global Organization for EPA and DHA (GOED) voluntary monograph
Molecularly distilled
Ultra-pure
Purified

Functional

Docosahexaenoic acid (DHA)

Docosahexaenoic acid (DHA) is a long-chain polyunsaturated omega-3 (n-3) fatty acid considered to be nutritionally essential to maintain optimal health. There are a number of known health benefits associated with omega-3 fatty acid intake, with most current research focusing on the n-3 fatty acids DHA and EPA (eicosapentaenoic acid). In the body, DHA is an important component of cell membranes, particularly in the brain and retina. However, the human body cannot synthesize omega-3 fatty acids on its own, so these nutrients must be provided by the diet. By consuming the n-3 fatty acid alpha-linolenic acid (ALA) from sources such as flax seed, the body can convert ALA into EPA and eventually DHA, but the low rate of conversion supports direct dietary intake of DHA from foods and dietary supplements 1. The major food sources of DHA, as well as EPA, are algae and cold-water oily fish, such as salmon, herring, mackerel, anchovies and sardines 2. Dietary supplements containing significant amounts of EPA and DHA are typically fish oils derived from these fish. In addition, infant formulas often contain supplemental DHA. The U.S. Food and Drug Administration (FDA) has determined that the use of DHA and EPA omega-3 fatty acids as dietary supplements is safe, provided that the daily intakes of DHA and EPA do not exceed 2 grams per day from dietary supplement sources such as fish oil 3. A major safety concern is the possible presence of heavy metals and toxins, which can be found in relatively high levels in fresh fish and unpurified fish oils. When considering omega-3 DHA and EPA dietary supplements, it is important to look for fish oils that have been purified to reduce the levels of these contaminants.
Eicosapentaenoic acid (EPA)

Eicosapentaenoic acid (EPA) is a long-chain polyunsaturated omega-3 (n-3) fatty acid considered to be nutritionally essential to maintain optimal health. There are a number of known health benefits associated with omega-3 fatty acid intake, with most current research focusing on the n-3 fatty acids EPA and DHA (docosahexaenoic acid). In the body, EPA is an important component of cell membranes where it can be used to generate signaling molecules called eicosanoids or can be converted into DHA. However, the human body cannot synthesize omega-3 fatty acids on its own, so these nutrients must be provided by the diet. By consuming the n-3 fatty acid alpha-linolenic acid (ALA) from sources such as flax seed, the body can convert ALA into EPA, but the low rate of conversion supports direct dietary intake of EPA from foods and dietary supplements 1. The major food sources of EPA, as well as DHA, are algae and cold-water oily fish, such as salmon, herring, mackerel, anchovies and sardines 2. Dietery supplements containing significant amounts of EPA and DHA are typically fish oils derived from these fish. The U.S. Food and Drug Administration (FDA) has determined that the use of EPA and DHA omega-3 fatty acids as dietary supplements is safe, provided that the daily intakes of EPA and DHA do not exceed 2 grams per day from dietary supplement sources such as fish oil 3. A major safety concern is the possible presence of heavy metals and toxins, which can be found in relatively high levels in fresh fish and unpurified fish oils. When considering omega-3 EPA and DHA dietary supplements, it is important to look for fish oils that have been purified to reduce the levels of these contaminants.
Mixed tocopherols

Mixed tocopherols are organic compounds collectively known as vitamin E. Natural tocopherols exist as a mixture of d-alpha-, d-beta-, d-gamma- and d-delta-isoforms, each having antioxidant activities 1. Tocopherols are present in many foods, such as vegetable oils, nuts and grains. They are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (21CFR182.3890) 2.
Omega-3 fatty acids

Omega-3 (n-3) fatty acids generally refer to the nutritionally essential polyunsaturated fatty acids (PUFAs) alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). Fatty acids are the building blocks of lipids, making them important sources of energy for the body and the main components of cell membranes 1. There are a number of known health benefits associated with omega-3 fatty acid intake, with most current research focusing on the longer chain n-3 PUFAs EPA and DHA. However, the human body cannot synthesize n-3 fatty acids on its own, and so these nutrients must be provided by the diet 1. Food sources of ALA include flax seed, hemp seed, walnut, canola, soy bean, and dark green leaves, while the major sources of EPA and DHA are algae and cold-water oily fish, such as salmon, herring, mackerel, anchovies and sardines 2.
Dietary unsaturated fatty acids are well absorbed through the intestine and into the bloodstream. The Institute of Medicine has established an adequate intake of 1.6 g/day ALA for men and 1.1 g/day ALA for women 1. The body can form EPA and DHA from ALA, but the low rate of conversion supports direct dietary intake of EPA and DHA. The U.S. Food and Drug Administration (FDA) has determined that the use of EPA and DHA omega-3 fatty acids as dietary supplements is safe, provided that the daily intakes of EPA and DHA do not exceed 2 grams per day from dietary supplement sources such as fish oil 3. A major safety concern is the possible presence of heavy metals and toxins, which can be found in relatively high levels in fresh fish and unpurified fish oils. When considering omega-3 EPA and DHA dietary supplements, it is important to look for fish oils that have been purified to reduce the levels of these contaminants.
Vitamin D3

Vitamin D3 (cholecalciferol) is a fat-soluble vitamin that is synthesized by humans in the skin when exposed to ultraviolet-B (UVB) rays from sunlight. Vitamin D3 is the most frequently recommended form of supplemental vitamin D 1. Current average daily intakes of vitamin D for Americans are well below suggested adequate intakes 2, and much of the world’s population is deficient in this important vitamin 3.
The main function of vitamin D is to regulate blood calcium and phosphorus concentrations by enhancing the efficiency of the small intestine to absorb these minerals. By influencing the absorption of calcium, vitamin D thus helps to form and maintain strong bones and teeth 4,5. Vitamin D supplementation helps prevent falls and maintain physical performance in the elderly 5,6. Adequate vitamin D intake may also be important for maintaining immune health 7,8, nervous system health 9, may help improve mood during the winter months (10),(11) and improve overall quality of life (12).
Vitamin D is generally well tolerated at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 600 international units (IUs) vitamin D for individuals ages 1-70 and 800 IUs for adults >70 years. RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. They serve as the basis for calculating the percent daily value (% DV) amounts found on dietary supplement and food labels.
According to the Endocrine Society’s Vitamin D Clinical Practice Guidelines, published in June 2011, individuals who are at risk for vitamin D deficiencies should as their physician to have their blood tested for the vitamin D metabolite [25(OH)D]. For individuals with blood 25(OH)D levels <75 nmol/L, higher amounts of vitamin D intake are suitable: children ages 1–18 may need 600–1,000 IU daily, adults >18 age may need 1,500–2,000 IU vitamin D daily (13).

Formulation

Kosher gelatin

Kosher gelatin. Gelatin is a protein derived from animal collagen, usually from cow or pig skin and bones. In order for a food to be classified as kosher, the ingredients, preparation and processing facilities must all meet kosher standards. Gelatin is a commonly used gelling agent in foods and can also be used to form hard or soft gelatin capsules for oral products 1. Gelatin is approved for use as a food additive by the U.S. Food and Drug Administration (FDA) 2.
Natural lemon flavor

Natural lemon flavor is oil extracted from the flavoring constituents of lemons, primarily the peels. Its significant function in food is flavoring rather than nutritional (21CFR501.22).
Purified fish oil concentrate

Purified fish oil concentrate. Commercial fish oils marketed as dietary supplements are typically derived from fresh, cold-water, oily fish, such as salmon, herring, mackerel, anchovies and sardines 1. The use of fish oil supplements is intended to provide the body with the essential omega-3 fatty acids, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). Concentrated fish oils tend to contain higher amounts of EPA and DHA. While consuming fatty fish can also provide these omega-3 fatty acids, most individuals do not consume the required servings. In addition, much of the available fish today is raised on farms rather than in their native water habitats, greatly reducing their concentrations of EPA and DHA. Furthermore, cold-water fish can contain dangerous amounts of environmental pollutants, such as mercury, PCBs (polychlorinated biphenyls) and dioxins 2. A major safety concern is the possible presence of these polluntants, which can be found in relatively high levels in fresh fish and unpurified fish oils. When considering omega-3 EPA and DHA dietary supplements, it is important to look for fish oils that have been purified to reduce the levels of these contaminants. The most common molecular distillation and steam deodorization techniques use a combination of pressure and high temperatures to remove environmental pollutants from fish oil supplements so that they may pass global regulatory standards 3.

Overall Product Benefits
- Helps [maintain/support] brain health and function*
- Supports healthy muscle function*
- Helps [maintain/support] cardiovascular health*
- Helps [maintain/support] heart health*
- Provides support for healthy triglyceride levels already within [normal levels/the normal range]*
- Helps maintain healthy blood lipid levels already within normal [levels/ranges]*
- Helps retain healthy blood lipid levels*
- Helps maintain healthy blood platelet function*
- May help regulate the production of interleukin-6 (IL-6) and prostaglandin E2 in healthy individuals*
- May help regulate the production of fatty acid derivative prostaglandin E2 by restoring a more healthy balance in the ratio of omega-6 to omega-3 fatty acids*
- May help regulate the production of the cytokine IL-6 in healthy individuals*
- May support a more healthy balance of immune functions*
- Supports a healthy inflammatory response*
- The vitamin D and omega-3 fatty acids EPA and DHA support a healthy inflammatory response^*
- Omega-3 and vitamin D intake can help keep your immune system in balance*
- Omega-3 and vitamin D intake can help maintain a healthy immune system*
- Contains vitamin D and omega-3 fatty acids for immune support*
Omega-3 Fatty Acid Benefits
- Source of omega-3 fatty acids, EPA and DHA, for the maintenance of good health*
- Supplies 1,110 mg EPA and DHA per day when taken as recommended
- Supplies 660 mg/day EPA when taken as recommended
- Supplies 450 mg/day DHA per day when taken as recommended
- Concentrated fish oil
- Highly concentrated EPA and DHA fatty acids
- Omega-3 intake helps support brain [health/function]*
- The omega-3 fatty acids EPA and DHA support a healthy inflammatory response*
- Studies indicate that EPA and DHA provide the brain health and development benefits provided by omega-3 fatty acid intake*
- Studies indicate that EPA and DHA provide the cardiovascular health benefits provided by omega-3 fatty acid intake*
- Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease. One serving of Mannatech’s Omega-3 with Vitamin D₃ provides 1110 mg EPA and DHA fatty acids. See nutrition information for total fat, saturated fat and cholesterol content.*
- Omega-3 intake in pregnant and lactating women may support normal development and functioning of the brain of the fetus and nursing infant*
Vitamin D Benefits
- Contains 830 IU vitamin D to support bone health*
- Vitamin D is important to bone health because it enhances calcium absorption*
- Vitamin D helps the body absorb calcium for strong bones and teeth*
- Vitamin D is essential for calcium absorption*
- Vitamin D contributes to the maintenance of healthy bones*
- Vitamin D regulates the blood concentrations of calcium and phosphorus
- The hormonal actions of vitamin D govern calcium balance within the body
- Vitamin D improves calcium absorption*
- A preferred source of supplemental vitamin D
- Vitamin D₃ is a natural form of vitamin D that is produced by the body
- A [highly/commonly] recommended form of supplemental vitamin D
- Vitamin D₃ is the form of supplemental vitamin D most often recommended
- Vitamin D₃ is believed to be the most beneficial form of supplemental vitamin D
- Vitamin D and its metabolites act as powerful immunoregulators*
- Vitamin D is an important contributor to musculoskeletal health*
- Vitamin D intake may help prevent falls and maintain physical performance in the elderly*
- Research suggests that vitamin D may play a role in maintaining nervous system health and function*
- Research shows that in addition to supporting bone health, adequate vitamin D intake may be important for maintaining immune health, nervous system health and overall quality of life*
- Vitamin D₃ helps improve mood/maintain positive mood [during the winter months]*
Omega-3 Fatty Acids Background
- Most American diets provide more than ten times as much omega-6 than omega-3 fatty acids, even though there is general scientific agreement that individuals should consume more omega-3 and less omega-6 fatty acids to promote good health
- Supplemental omega-3s can help reduce an imbalance in the ratio of omega-6 to omega-3 fatty acids often caused by the common Western diet
- Omega-3s are called essential fatty acids because the body cannot synthesize omega-3s
- Omega-3 fatty acids are nutrients essential to health and must be obtained through the diet*
- Humans are dependent upon dietary intake of omega-3s to get an adequate amount, a necessity for good health in people of all ages*
- EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are two omega-3 fatty acids that [are important to/contribute to] health*
- In evaluating the beneficial effects of omega-3 fatty acids, researchers have focused on EPA and DHA
- Alpha-linolenic acid (ALA), which is present in vegetable oils such as flaxseed and canola oils, is poorly converted to EPA and DHA in the body. Thus, direct dietary intake of these compounds is important.
- Omega-3 fatty acids include ALA, EPA and DHA. ALA is present in vegetable oils such as flaxseed and canola oils, whereas EPA and DHA are found in algae and fish oils. ALA is chemically the parent compound but the body does not efficiently convert it to EPA and DHA. Thus, direct dietary intake of EPA and DHA is important.
- Intake of omega-3 fatty acids has been identified as one of twelve modifiable behaviors (along with quitting smoking, lowering salt intake, etc.) that can contribute to increased longevity. A study showed that individuals with intake levels of 250 mg per day of EPA and DHA tended to live longer.*
- There is continuing scientific debate as to whether or not dietary omega-3 fatty acids contribute to weight loss. However, higher blood levels of omega-3 fatty acids are associated with a healthier body weight.*
- International experts suggest that individuals should aim to achieve an average daily intake of at least 650 mg of EPA and DHA combined, with at least 220 mg of each. The U.S. Institute of Medicine has not established an adequate intake level for omega-3 fatty acids but other countries, including Canada, Sweden, the UK, Australia and Japan, recommend intake of 300 to 500 mg per day of EPA and DHA.
- International experts suggest that pregnant and lactating women should aim to achieve an average daily intake of at least 200 mg DHA. This amount is thought to be sufficient to help support optimal visual and cognitive development in the fetus and nursing infant.* Mannatech’s Omega-3 with Vitamin D₃ supplies 450 mg DHA per day when taken as recommended.
Vitamin D Background
- Research suggests that high vitamin D [intake/blood levels] can support breast and colorectal health^*
- An estimated 70 percent of the U.S. population has diets deficient in vitamin D
- The typical American diet provides only about 30 percent of the recommended daily intake of vitamin D
- A deficiency in vitamin D will reduce the amount of dietary calcium that is absorbed by 10-15 percent
- Vitamin D deficiencies have reached epidemic status throughout the world
- The following populations are at risk for vitamin D deficiency:
- The major source of vitamin D is exposure to natural sunlight
- Insufficient sunlight is a well-known risk factor for vitamin D deficiency
- Human skin requires several minutes of regular and direct exposure to sunlight (UVB rays) in order to produce vitamin D₃. Dark skin, sunblock use, and insufficient sun exposure (due to limited outdoor activity, seasonal/temporal/atmospheric factors, and geographic latitude) have all been associated with lower circulating hydroxyvitamin D levels
- Very few foods naturally contain or are fortified with vitamin D
- Vitamin D deficiency in the elderly increases the risk of bone fracture
- The National Academy of Science’s Institute of Medicine (IOM), which sets the Daily Reference Intakes for the U.S., has set the Recommended Dietary Allowance (RDA) for vitamin D at 600 IU per day for all life stages with the exception of people over 70 years old for which the RDA is 800 IU per day. The IOM Committee found that vitamin D blood levels of 20 ng/ml 25 (OH)D are sufficient for bone health. Vitamin D deficiency was defined as serum levels below this amount.
- An international group of vitamin D experts in The Endocrine Society challenged the IOM findings, suggesting that vitamin D insufficiency be defined as 25 (OH)D levels of 21-29 ng/ml and sufficiency as levels of 30-100 ng/ml (75-250 nmol/L).
- The Endocrine Society suggested the Upper Limit (UL) be 10,000 IU for adults and 4,000 IU for children ages 1-18, rather than the 4,000 IU to 2,500 IU UL’s set for these age groups by the IOM.
- The Endocrine Society Task Force finds that, although 400 to 600 IU/day vitamin D may be sufficient for children aged 0-1 year and 1 to 18 years, an amount of 1,000 IU/day may be required to raise blood levels of 25(OH)D above 30 ng/ml.
- The Endocrine Society Task Force finds that, although adults 19-50 years require at least 600 IU/day, 1,500-2,000 IU vitamin D/day may be required to raise blood levels of 25(OH)D above 30 ng/ml.
Omega-3 Fatty Acid and Vitamin D Background
- Omega-3 fatty acids and vitamin D are both required nutrients. There is significant evidence that much of the world’s population is deficient in both nutrients.
- There are a limited number of foods that are naturally rich in vitamin D and/or omega-3 fatty acids. Fish is one such source, but given concerns that certain types of fish can be contaminated with ocean pollutants, especially mercury, it is advised to limit consumption of fish known to be lower in mercury, such as salmon, to only 2 servings (12 oz.) per week.

Multiple Product Open-Label Clinical Trial (2013)
In a six-month, open-label human studyof 15 retired football players, intake of Mannatech products resulted in statistically significant improvements in numerous self-reported measures of physical and mental health, quality of life, memory, and elbow and knee pain reduction. Study participants took Mannatech’s Ambrotose^® complex powder, Omega–3 with Vitamin D3 capsules, Ambrotose AO^® capsules, PhytoMatrix^® caplets and PLUS^™ caplets. All of these products are gluten-free and NSF-certified. Authors include Mannatech scientists Drs. Robert A. Sinnott and Rolando L. Maddela, Dr. Sejong Bae of the University of North Texas Health Science Center and Dr. Talitha Best of the University of South Australia, Adelaide.

Sinnott RA, Maddela RL, Bae S, Best T. (2013) The effect of dietary supplements on the quality of life of retired professional football players. Global J Health Sci 2(5):13-26.
- Read abstract
This article can also be accessed from PubMed.

Omega-3 With Vitamine D3

Omega 3 with Vitamine D3 from Mannatech is one of the purest Omega 3 of the world.

Order now